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課程名稱 |
質譜儀及其應用
MASS SPECTROMETRY AND ITS APPLICATION |
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開課學期 |
96-2 |
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授課對象 |
理學院 化學所化學組 |
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授課教師 |
陳仲瑄 |
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課號 |
Chem5054 |
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課程識別碼 |
223 U2510 |
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班次 |
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學分 |
3 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期五6,7,8(13:20~16:20) |
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上課地點 |
新401 |
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備註 |
外系所學生選修需經授課教師同意。本課程中文授課,使用英文教科書。?
限學士班三年級以上
總人數上限：60人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/962mass |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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課程概述 |
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課程目標 |
Outline on Mass Spectrometry Course Chung-Hsuan Chen I. Introduction: I.a Basic of Mass Spectrometry I.b Major Applications of Mass Spectrometry I.c Vacuum Science and Technology II. Ionization: II.a Electron Ionization II.b Chemical Ionization II.c Photoionization II.d Matrix-assisted Laser Desorption/Ionization II.e Electrospray Ionization II.f Other Ionization methods: FAB, Field Ionization, SIMS etc. II.g Major challenges for Future Development III. Mass Analysis: III.a Quadrupole III.b Ion Trap III.c Time-of-flight III.d Magnetic Sector III.e FTICR III.f Major Challenges for Future Development IV. Detection: IV.a Charge Collector IV.b Charge Amplifier Detector IV.c Scientillator Detector IV.d Other Detectors and Major Barriers to Overome. V. Tandem Mass Spectrometry V.a Basic of MS/MS V.b Collision induced Dissociation V.c Ion-Molecule Interaction VI. Chromatography/Mass Spectrometer Coupling VI.a GC/MS VI.b LC/MS VI.c CE/MS VII Biomolecule Analysis VII.a Oligonucleotide, Protein, Polysaccharide Analysis VII.b DNA Analysis and Sequencing VII.c Proteomic & Metabolomic Applications VII.d Disease Diagnosis VIII Other Applications VIII.a Trace Element Analysis VIII.b Organic Polymer Analysis VIII.c Environmental Application VIII.d Material Analysis IX Future Challenges: IX.a Ionization Mechanism IX.b Mass to Charge Ratio Extension IX.c Quantitative Measurements IX.d Dynamic Range Extension IX.e Cost Reduction IX.f Size Reduction X. Conclusion |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
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評量方式
(僅供參考) |
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